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Liquid Manganese


T. J. Clark Liquid Manganese: 

Manganese (Mn) is an essential trace mineral that is concentrated
primarily in the bone, liver, pancreas, and brain. This mineral is a
component of several enzymes: (1) Mn-superoxide dismutase which
prevents tissue damage due to lipid (fat) oxidation; (2) pyruvate
carboxylase which helps break down carbohydrates; and (3) arginase
which is important for nitric oxide synthesis and the formation of urea in
the urine. Manganese also activates numerous enzymes, particularly
glycosyltransferases which are involved with the formation of cartilage in
bone and skin. 

IMPORTANCE: An antioxidant nutrient; important in the blood
breakdown of amino acids and the production of energy; necessary for
the metabolism of Vitamin B-1 & Vitamin E; Activates various enzymes
which are important for proper digestion & utilization of foods; is a
catalyst in the breakdown of fats & cholesterol; helps nourish the nerves
and brain; necessary for normal skeletal development; maintains sex
hormone production. 

Deficiencies: In animals manganese deficiencies produce abnormalities
in brain function, glucose tolerance, reproduction, and skeletal and
cartilage formation. In humans, gross deficiencies have not been
documented in free-living populations but deficiencies created in a
metabolic unit suggest the mineral is important to maintain the integrity of
the skin, bone and menstrual cycle, and in cholesterol metabolism.
Certain population groups have been reported to have suboptimal
status, including children with birth defects or on long-term total
parenteral nutrition and patients with Perthes' disease, hip dislocations in
Down's syndrome, osteoporosis, multiple sclerosis, non-trauma
epilepsy, senile cataracts, acromegaly, and amyotrophic lateral sclerosis.
May result in paralysis, convulsions, dizziness, ataxia, loss of hearing,
digestive problems, blindness and deafness in infants.

Diet recommendations: The Estimated Safe and Adequate Dietary
Intakes (ESADDIs) for Mn each day are 2.0-5.0 mg for adults. For
children, ESADDIs are 1.0-1.5 mg for ages 1-3 yrs; 1.5- 2.0 mg for
ages 4-6 yrs, 2.0-3.0 mg for ages 7-10 yrs, and 2.0-5.0 for ages 11-14
yrs. Recent research suggest that recommendations for formula-fed
infants are 0.005 mg/day and 0.030 mg/day for breast-fed infants. 

Usual dietary intakes in the U.S. are about 2.2 and 2.8 mg/day for adult
women and men, respectively. However, much higher intakes (10-18
mg) are found with vegetarian diets and those based on whole-grain
products. Thus, the current ESADDI may be too conservative for

Food sources: Excellent sources of manganese (>1 mg/serving) include
pecans, peanuts, pineapple fruit and juice, oatmeal, shredded wheat and
raisin bran cereal. Good sources (> 0.5 mg/serving) are beans (pinto,
lima, navy), rice, spinach, sweet potato, and whole wheat bread. Very
little Mn is found in meat, poultry, fish, milk, dairy products or sugary
and refined foods. 

Dietary components that may adversely affect manganese absorption,
retention or excretion include iron, phosphorus, phytates, fiber, calcium,
copper, and polyphenolic compounds. 

Toxicity: Toxicity has occurred from industrial exposure, such as miners
breathing manganese dust and drinking contaminated well water.
Symptoms of toxicity are the development of a schizophrenia with
nervous disorders resembling Parkinson's disease. The reference dose
(RfD) set by the EPA in 1993 is 10 mg/day for a 70 kg body weight;
this dietary level is considered to be without significant risk of a
deleterious effect for a lifetime of exposure. There is no evidence of
toxicity occurring from ingestion of typical diets. For drinking water, the
RfD is 0.2 mg Mn/L. 

Recent research: Lower manganese bloods levels have been observed
in patients with osteoporosis, non-trauma epilepsy and Perthes' disease.
Low dietary levels of manganese that lower the levels of Mn-superoxide
dismutase may increase colon cancer susceptibility. Magnetic resonance
imaging (MRI) is a very sensitive technique that can detect toxic
accumulation of Mn in the brain.


Supplement Facts

Serving Size: 1 Teaspoon (5ml)

Serving Per Container: 47



per serving


Calories 4 <2
Total Carbohydrate 1 g <2
Total Fat 0 g 0
Sodium 0 g 0
Manganese 2 mg **
Phytogenic Mineral Catalyst

100 mcg


Calcium, Chloride, Cobalt, Chromium, Magnesium, Boron, Manganese, Molybdenum, Selenium, Iron, Copper, Phosphorus, Sulfur, Potassium, Iodine and Zinc

* Percent Daily Values based on a 2,000 calorie diet

** No daily value established

Directions: Take 5 ml once daily with food

* This statements have not been evaluated by the Food and Drag Administration.

This products are not intended to diagnose, treat, cure or prevent any disease.



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*These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.

The information on this site is not meant to serve as a medical prescription for you. It is intended to be used only for informational purposes. This information is not a substitute for advice provided by your own health care provider. You should always consult with a medical professional before taking any new dietary supplement